This test system detects the RHCE alleles RHCE*C, *c, *E, *e, as well as the SNP c.122A>G (CW), and SNP c.733C>G. Based on the exon pattern via detection of RHD exons 1-7, as well as 9, and 10, a variety of RHD categories and hybrid genes are uniquely characterized. In addition, RHD null alleles and further partial Ds (separation of the DAU allele cluster) are identified via specific SNPs.