The present detection system allows the typing of the rare blood group alleles Diego (DI*01/DI*02), Wright (DI*02.03/DI*02. 04), Cartwright (YT*01/YT*02), Lutheran (LU*01/LU*02), Kell (KEL*02.03 and KEL*02.06), Colton (CO*01.01/CO*02.01), Knops (KN*01/KN*02), and Landsteiner-Wiener (LW*05/LW*07). The blood group systems mentioned are biallelic with one common and one rare allele each.